Seems a number of people are pretty pissed at 3DRealms for not having a singleplayer port for linux.

http://forums.3drealms.com/vb/showthread.php?t=16629

I suspect the game developers are going to be hearing alot more from the linux camp as it grows in popularity and Prey might just be the opening salvo. There's valid points on both sides but all the discussion should be moot once linux hits critical mass.