1UP has an exclusive preview (with screenshots!) of DeathSpank, Ron Gilbert's new game.
It's not confirmed on Linux yet (it's actually not confirmed for any platforms at the moment) but it is being developed by Hothead Games, so there's at least a good chance we'll see a port.
I liked the PennyArcade-games very much (though I felt they were a bit short), and of course I just loved Monkey Island.
So this has to be good. Let's hope they'll still support linux.