With wine 1.2 RC and fglrx 10.5 I got a tremendous improvement in Guild Wars.
With wine 1.1.44 and fglrx 10.4 I got graphic corruptions in almost all the areas.
Now I got no corruption at all and I am able to run it in highest settings with descent fps. I don't if it was wine 1.2 RC or fglrx 10.5, but guild wars just runs awesome now on fglrx. I also got a quite big speed improvement.