Well, I wasn't sure it'd run on my little card (radeon3650), but it's quite playable, about 20fps windowed mode with max settings (little lower if there's plenty of action on the screen), and about 30fps with lowered settings. The originally cheapo replacement card has some life left in it yet.
Had to setup 32bit sdl emulation lib (kudos dimko), but haven't had any game crashes as of yet. Works well with the rest of my system in windowed mode, for which I'm very thankful. Good to have a game just running on the side that doesn't mind if the cursor wanders off for other tasks for a while.