It seems I been rather lucky with Catalyst Drivers, because my last 2 purchases of graphics cards (HD 3850 and hd 7850) has worked fine for me with Catalyst, i do not know if it is a big difference between brands because both card was from Sapphire, and my next card will probably also be from Sapphire because of this.
What nvidia driver do you use? xrandr changed with 300 series.
The video orientation is correct once the desktop is logged into, but not before. Example the login screen puts the secondary monitor on the right, when I have it set as above. Since I use LightDM I may have to set the monitor also up in Gnome?