Quote Originally Posted by Del_ View Post
The threading optimization is simply nvidia implimenting a hack that has been floating around for World of Warcraft in wine. You find the history of it here:
http://bugs.winehq.org/show_bug.cgi?id=11674

From that thread it is clear that this issue is special for WoW, but may also be of interest to Guild Wars 2. I can confirm that the patch does wonders for WoW on linux with wine, just as intended.

Thanks for the thourough testing, it confirms that this really is a special issue for WoW, while earlier indications were more anecdotal in nature.
What version of the game are you running? Are you running current or 2.4.3/3.3.5a/4.0.6a